The Relationship Between Neuropathic Pain, and the Function of the Upper Limbs Based on Clinical Severity According to Electrophysiological Studies in Patients with Carpal Tunnel Syndrome

Motoki Sonohata*, 1, Toshiyuki Tsuruta 2, Hiroko Mine 2, Tadatsugu Morimoto 1, Masaaki Mawatari 1
1 1Department of Orthopaedic Surgery, Faculty of Medicine, Saga University, 5-1-1 Nabeshima, Saga 849-8501, Japan
2 2Tsuruta Orthopaedic Clinic, 1241-6 KatsuUshizu-Machi, Ogi City, Saga 849-0306, Japan

Article Metrics

CrossRef Citations:
Total Statistics:

Full-Text HTML Views: 783
Abstract HTML Views: 400
PDF Downloads: 251
Total Views/Downloads: 1434
Unique Statistics:

Full-Text HTML Views: 481
Abstract HTML Views: 280
PDF Downloads: 162
Total Views/Downloads: 923

Creative Commons License
© Sonohata et al.; Licensee Bentham Open.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution License ( which permits unrestrictive use, distribution, and reproduction in any medium, provided the original work is properly cited.

* Address correspondence to this author at the Department of Orthopaedic Surgery, Faculty of Medicine, Saga University, Saga 849-8501, Japan; Tel: +81-952-34-2343; Fax: +81-952-34-2059; E-mail:


Carpal tunnel syndrome (CTS) is an entrapment neuropathy of the median nerve, and CTS can cause neuropathic pain. The aim of this study was to evaluate the relationship between neuropathic pain, function of the upper limb, and the electrophysiology in patients with CTS. The terminal latency of median nerve was measured in 34 patients diagnosed with CTS, and they were asked to fill out the Japanese Society for Surgery of the Hand version of the Disability of Arm, Shoulder, and Hand questionnaire (DASH-JSSH) as the patient’s assessment of the function of upper limbs and pain DETECT as an assessment for neuropathic pain. There was no significant correlation between the terminal latency and the pain DETECT score, or the terminal latency and the DASH-JSSH score. However, there was a significant correlation between the pain DETECT and DASH-JSSH scores. Neuropathic pain affects the function of the upper extremities in patients with CTS.

Keywords: Neuropathic pain, carpal tunnel syndrome, quality of life, painDETECT, electrophysiology, median nerve, terminal latency.