Few Adverse Reactions to Metal on Metal Articulation in Total Hip Arthroplasty in a Review Study on 358 Consecutive Cases with 1 to 5 Years Follow-Up

Jens Stürup*, 1, Line B Dahl1, Karl-Erik Jensen2, Anne-Birgitte Larsen3, Peter Gebuhr3
1 Orthopaedic Department U, 2162, Rigshospitalet, University of Copenhagen, Denmark
2 Department of Radiology, Rigshospitalet, University of Copenhagen, Denmark
3 Orthopaedic Department, Hvidovre Hospital, University of Copenhagen, Denmark

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© Stürup et al.; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Orthopaedic Department U, 2162, Rigshospitalet, University of Copenhagen, Denmark, Blegdamsvej 9, 2100 Copenhagen Ø, Denmark; Tel: +4521483713; E-mail:


The aim of the present study was to determine the frequency of adverse reaction to metal on metal total hip arthroplasty using a M2a-38 articulation and a Magnum articulation, (Biomet Warsaw, Indiana).

All patients who had received a Metal on Metal bearing prosthesis, in two centres in Copenhagen, were asked to complete a questionnaire about groin pain. Patients with self-reported groin pain, 68/314, underwent a physical examination and had Co and Cr ion levels measured in full blood samples. Fifty patients also had a CT scan performed.

The present study found one patient with bilateral arthroplasty, who had an adverse reaction on one side. In addition the study showed that females had higher values of Co and Cr, and that younger patient reported groin pain more often.

The conclusion of this study is that the number of adverse reactions is low, despite the time of observation being relatively short, no high frequency of adverse reactions to this prosthesis is expected.

Keywords:: Metal on metal, hip, ALVAL, Pseudotumor.