RESEARCH ARTICLE

Hyperbaric Oxygen for Osteomyelitis in a Compromised Host

The Open Orthopaedics Journal 3 May 2013 RESEARCH ARTICLE DOI: 10.2174/1874325001307010114

Abstract

Post-traumatic osteomyelitis is a rare but debilitating complication of closed fractures. Most infections can be resolved with aggressive debridement, intravenous antibiotics, and hardware removal. However, the eradication of infection can be challenging in a patient with multiple comorbidities. Refractory infection may require suppressive therapy or amputation to control the disease. Improvements in care have led to improved survival for this population, posing new challenges in their post-traumatic care. We report on the successful use of hyperbaric oxygen therapy as an adjunct in a compromised host with recurrent post-traumatic osteomyelitis despite aggressive debridement, removal of instrumentation, and several courses of intravenous antibiotic therapy. Hyperbaric oxygen may be considered as an adjunct to standard treatment protocols for refractory osteomyelitis in compromised hosts.

Keywords: Hyperbaric oxygen, infection, trauma, osteomyelitis, vascular disease.
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