Sacroiliac Joint Arthrodesis-MIS Technique with Titanium Implants: Report of the First 50 Patients and Outcomes

Leonard Rudolf*
Alice Peck Day Memorial Hospital, 129 Mascoma Street, Lebanon, NH 03766, USA

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© Leonard Rudolf; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Alice Peck Day Memorial Hospital, 129 Mascoma Street, Lebanon, NH 03766, USA; Tel: 603 448 6344; Fax: 603 448 3405; E-mail:


This retrospective study of 50 consecutive patients treated by a single orthopedic spine surgeon in private practice was conducted to evaluate the safety and efficacy of minimally invasive sacroiliac joint fusion using a series of triangular, porous plasma spray coated titanium implants.

Medical charts were reviewed for perioperative metrics, complications, pain, quality of life and satisfaction with surgery. All patients were contacted at a 24 months post-op to assess SI joint pain, satisfaction with surgery and work status.

An early and sustained statistically significant improvement in pain function was identified at all post-operative time points (ANOVA, p<0.000). A clinically significant improvement (>2 point change from baseline) was observed in 7 out of 9 domains of daily living. The complication rate was low and more than 80% of patients would have the same surgery again.

MIS SI joint fusion appears to be a safe and effective procedure for the treatment of sacroiliac joint disruption or degenerative sacroiliitis.

Keywords: Arthrodesis, minimally invasive surgery, sacroiliac joint.


Undertreated or unrelieved pain results in over $60 billion dollars in lost income, medical expenses and lost productivity [1]. Up to 90% of adults experience back pain in their lifetime and back pain is the second most common reason for visits to primary care physicians [2]. Identifying the pain generator in patients reporting low back pain is a significant challenge. Pain from the sacroiliac (SI) joint can mimic discogenic or radicular low back pain and can present as low back, sacral, hip, pelvic, groin or gluteal pain, leading to the potential for inaccurate diagnosis and treatment [2-4]. Further, SI joint conditions have been cited as a possible cause of failed back surgery syndrome [5, 6]. In a large retrospective study of 1,293 patients with low back pain published in 1987, Bernard and Kirkaldy-Willis found a 22.5% prevalence rate of SI joint pain in patients presenting with low back pain [7]. Other authors have described similar findings, reporting an SI joint pain prevalence rate of 15-30% in patients with low back pain [4, 8]. Additionally, the SI joint seems to be affected by altered biomechanics after lumbar spinal fusion. Literature indicates 40% of post-lumbar and lumbosacral fusion patients have SI joint pain and up to 75% of these patients develop radiographically detectable SI joint degeneration after 5 years [9-11].

Treatment options for patients with SI joint pain have focused on physical therapy and pain management including: medication optimization, physical therapy, SI joint injections, and radiofrequency ablation. For patients with long standing SI joint symptoms refractory to non-surgical treatment, traditional open SI joint fusion surgery is an option. Open arthrodesis procedures reported in the literature require relatively large incisions, significant bone harvesting, and lengthy hospital stays; moreover, they require non-weight bearing for several months [12-15]. The recent trend in spine surgery has been to explore minimally invasive surgical (MIS) approaches to common pathology. Recent publications of percutaneous placement of ileosacral screws or threaded cages report relatively good clinical results [16, 17].

The purpose of this retrospective study is to evaluate the safety and effectiveness of an MIS SI joint fusion treatment using a series of triangular, porous plasma spray coated titanium implants placed across the SI joint. The objective of this surgery is to achieve arthrodesis through a permanent linkage across the joint, relying on bone ongrowth for permanent stabilization of the implant.


We report treatment outcomes of the first 50 consecutive patients treated at a single, community based spine practice between October 2007 and July 2010. The medical charts of all 50 patients were reviewed for complications, pain, quality of life, satisfaction with surgery and return to work status up to 12-month follow up. At a minimum of 24 months post-operatively, all patients were contacted via telephone by the treating surgeon to assess SI joint pain, satisfaction with surgery and return to work status.

Mean age at the time of surgery was 54 years (range 24-85) and most (68%) patients were women (Table 1). Twenty two (44%) patients had a history of previous lumbar spine fusion. Eight (16%) patients had ongoing symptomatic lumbar spine pathology managed using conservative care.

Table 1.

Demographic Information

Patients 50
Age 54 (range 24-85)
Gender 34F (68%), 16M (32%)
Prior lumbar fusion 22 (44%)
Presence of lumbar pathology treated non-surgically 8 (16%)

Patients were diagnosed with either degenerative sacroiliitis or sacroiliac joint disruption using a combination of history, clinical exam, and positive diagnostic injection. All patients presented with chronic lower back pain refractory to prolonged conservative care. The most common chief complaint was posterior pain located close to the SI joint. A thorough physical and clinical exam was performed on all patients, emphasizing the lumbar spine, SI joint and hip axis. Provocative physical examination maneuvers were used to guide subsequent diagnostic activities. All patients with suspected SI joint pain underwent imaging with X-ray, CT and/or MRI to evaluate SI joint pathology and exclude lumbar spine and hip pathology. When clinical, physical and radiographic examinations were concordant, patients were sent for confirmatory image-guided injections of the SI joint. A 75% reduction in pain, as measured on a visual analog scale, immediately following injection of local anesthetic was used to confirm the SI joint as the pain generator [11].

MIS SI joint fusion using the iFuse Implant System (SI-BONE, Inc., San Jose, CA) was performed in all cases by a single orthopedic spine surgeon. The surgical technique involves placing three porous plasma coated titanium implants across the SI joint.

Implant Description

The triangular shape of the titanium implant combined with an interference fit is designed to minimize rotation, micromotion, and avoid issues often seen with orthopedic screws, such as loosening and breakage [18]. The implant surface is prepared with a porous plasma spray coating, allowing for bone ongrowth across the joint, resulting in permanent fusion to the implants. The larger implant surface area and increased strength compared to a threaded screw is designed to maximize post-surgical weight bearing capacity. Biomechanical studies demonstrate the implant is 3 times stronger in shear and bending strength compared to an 8mm cannulated screw (SI-BONE Inc. data on file). Implants are available in either a 4.0 or 7.0mm inscribed diameter and in 5mm incremental lengths from 30mm to 70mm to fit individual patient anatomy.

Surgical Technique

The procedure is performed under general anesthesia with the patient in the prone position. The lateral buttock and pelvis is prepped to allow a 3cm skin incision. The gluteal fascia is penetrated bluntly and the muscle is split longitudinally to gain access to the outer table of the ilium. A Steinmann pin is placed through the ilium across the SI joint into the lateral portion of the sacrum (Denis zone I – Fig. 1) and lateral to the neural foramen [19]. The entire procedure is monitored using lateral, inlet, and outlet views on fluoroscopy. A depth gauge is used to determine implant length. Through the cannulated tissue protector, bone is prepared using a drill and triangular broach before the implant is inserted. The cephalad implant is routinely placed within the sacral ala (Fig. 2). A pin-guide system is used to facilitate placement of the subsequent implants. The second implant is generally located above or adjacent to the S1 foramen and the third between the S1 and S2 foramen (Denis zone I) (Figs. 3, 4). The incision is then irrigated and the tissue layers are closed with Vicryl and Monocryl.

Fig. (1).

Denis zones.

Fig. (2).

Fluoroscopic image of the first implant placed over the Steinmann Pin.

Fig. (3).

AP fluoroscopic image of all 3 implants in place.

Fig. (4).

Lateral fluoroscopic image of all 3 implants in place.

In the reported cohort, 4 implants were placed unilaterally in one patient and bilaterally in another. Two short female patients received 2 implants each. All other patients received 3 implants. Four patients returned to have the contralateral side treated due to progressing symptoms and 1 patient underwent bilateral SI joint surgery on the same day.

Patients were required to use crutches for a period of time before resuming full activity. CT scans were performed immediately post-operatively and at the 6- or 12-month visit to assess implant status. An independent radiographic review of images acquired at the 6-month interval showed 95% of patients with boney ongrowth [20].

Functional Outcome Assessment

Pain and functional outcomes were assessed pre-operatively and post-operatively at 3-, 6-, and 12-month follow-up visits using a novel patient outcomes questionnaire (Table 2). This outcomes instrument was created in order to reduce the burden of completing multiple lengthy questionnaires on patients and staff in this private practice setting. Questions were pulled from several validated instruments including SF-36 and Oswestry Disability Index. The survey asked patients to rate their pain and function in 9 domains as well as satisfaction with surgery and work status. A simple numerical rating scale (NRS) of 0-10 with 0 representing no pain or difficulty and 10 representing the worst pain imaginable or complete incapacitation was used for all domains.

Table 2.

Quality of Life Questionnaire

1. How much pain are you in at this time? (Questions 2,3,4) How well are you able to perform:
2. Light activities like walking a block or dressing yourself?
3. Moderate activities like playing golf, walking half a mile, or dancing?
4. Vigorous activities like running or moving furniture?
5. How much is your sleep disturbed by pain at this time?
6. How well are you able to lift items off the floor at this time?
7. How would you assess your level of happiness at this time?
8. How interested are you in socializing at this time?
9. Because of pain, how much is your socializing limited at this time?

In addition, all patients were contacted after a minimum of 24 months post-operatively via telephone to assess SI joint pain using a 0-10 NRS, work status, and satisfaction with surgery.


We report on the first consecutive 50 patients treated with minimally invasive SI joint fusion by a single surgeon. Four (8%) patients underwent concomitant lumbar spine procedures at the time of SI joint fusion surgery. A total of 37 right-sided SI joints and 18 left sided joints were fused (Table 3). Average (± SD) operating time was 65 ± 26 minutes and blood loss was minimal (<50cc) in all cases.

Table 3.

Peri-Operative Characteristics

Joints treated 55
Right SI joint 37
Left SI joint 18
Bilateral surgery in one setting 1
Staged bilateral fusion 4
OR time (min) 65 ± 26
Prior lumbar fusion 22
Presence of lumbar spine pathology treated non-surgically 8
Concomitant lumbar surgery 4


There were 10 peri-operative complications. Three patients who had subcuticular skin closure developed superficial cellulitis that resolved after a short course of oral antibiotics. No infections occurred after using Nylon skin sutures. One patient experienced a deep-soft tissue wound infection with gram-negative organism that resolved after 6 weeks of intravenous antibiotics. Two patients experienced a large buttock hematoma, with post-operative pain and difficulty sitting. Resolution was noted after 4-6 weeks, without residual symptoms.

Implant penetration into the sacral neural foramen was discovered on post-operative pelvic CT scan in 2 patients. Clinical exam revealed nerve root irritation and radicular pain without neurological deficit. Both patients were brought back to the OR and the misplaced implants were retracted to the edge of the neural foramen, resulting in complete resolution of symptoms.

In one patient with an unrecognized hemi-sacralized L5 transitional vertebrae, the first implant was inadvertently placed too cephalad, compressing the L5 nerve. This patient was brought back to the OR for a partial retraction of the implant and experienced a complete resolution of symptoms.

One patient had a non-displaced fracture located at the inferior edge of the ilium adjacent to the sciatic notch at the edge of the lowest implant. The fracture healed without intervention. CT scans performed at 12 months on all 10 patients revealed evidence of bone ongrowth with no suggestion of implant loosening.

One late complication occurred. Three years after surgery, a patient presented with persistent and gradually increasing SI joint pain. CT of the pelvis showed findings suggestive of motion surrounding the sacral end of the 2 most caudal implants, which were noted to be positioned posteriorly rather than central and anterior in the sacroiliac joint. A CT-guided injection confirmed the SI joint as the pain generator. Two additional 7.0mm implants were placed anteriorly to the loosened implants, resulting in complete symptom resolution.

Clinical Outcomes

Of 50 patients treated, quality of life questionnaires were available for 49 patients pre-operatively, 41 patients at 3-months, 40 at 6-months and 27 at 12-months. Results for the 4 patients who underwent concomitant lumbar spine procedures were excluded from analysis. A repeated analysis of variance (ANOVA, PROC MIXED) was performed using SAS version 9.0 (Cary, NC) to evaluate change in pain and function across post-operative time points. Clinical significance was defined as an improvement of 2 points from baseline [21].

Patients showed an early and sustained clinically and statistically significant improvement in 7 out of 9 domains at all time points (Table 4). The most dramatic improvement was observed in pain with scores decreasing by 3.92, 4.36, and 4.29 points at the 3-, 6-, and 12-month intervals respectively (p<0.0001). The percentage of individual patients who experienced a clinically significant benefit was 78%, 85%, and 71% at the respective intervals. The ability to perform activities, regardless of perceived difficulty (light, moderate or vigorous) showed early and continued improvement; though there were no statistically significant differences across postoperative follow up time points (p<. 0001). Sleep disturbance caused by pain showed an early and durable improvement, decreasing by an average of 3 points at all postoperative visits (p<0.0001). Compared to baseline, there was a statistically significant improvement in overall happiness at all time points (p=0.002). The reported effect of pain on patient’s social life improved at all three time points (p<0.001). Scores for lifting ability and general social interest showed little to no improvement from baseline at all time points. Patient-reported satisfaction with treatment was high: 91% of patients at 3-months, and 82% at 6- and 12-months would have the same surgery again.

Table 4.

Results: Quality of Life Outcomes

Baseline 3 Month (n=44) 6 Month (n=41) 12 Month (n=27) ANOVA
Mean Mean SD Mean SD Mean SD p
Pain 7.6 -3.92 2.75 -4.36 2.60 -4.29 3.35 <.0001
Light activities 5.6 -2.09 2.90 -2.44 2.72 -2.61 3.01 <.0001
Moderate activities 7.8 -1.88 3.58 -3.5 3.61 -2.59 4.01 <.0001
Vigorous activities 8.8 -1.28 3.54 -2.85 4.08 -2.30 4.52 0.0081
Sleep 6.8 -3.17 3.16 -3.26 3.07 -3.04 3.77 <0.0001
Lifting 5.9 -0.81 3.51 0.05 3.08 -0.09 4.26 0.326
Overall happiness 6.3 -1.91 3.88 -2.49 3.52 -2.39 3.37 0.0022
Social Interest 5.2 -0.32 3.96 0.59 4.22 0.36 4.16 0.4968
Pain affect on social interest 7.1 -3.43 3.68 -3.85 3.57 -3.82 3.66 <.0001

We attempted to contact all 50 patients at a minimum 24-month follow up via telephone to assess SI joint pain, satisfaction with surgery and return to work status. Forty-five patients were available for follow up: three patients were lost to follow up and two patients died, both from unrelated conditions. Mean follow up was 40-months (range 24-56 months). The mean (±SD) pain score was 2.0 (2.8) with 82% of patients reaching MCID (>2 point change). Compared to baseline, the mean improvement was 5.59 (3.5 SD) points, representing a clinically and statistically significant (p<. 0001) improvement. Although pain scores were lowest at this time point, a repeated analysis of variance analysis revealed no statistically significant difference across various postoperative time points (p=0.10). All patients who reached MCID, and none who did not, reported satisfaction with surgery (82%), indicating that satisfaction was correlated with symptom improvement. At baseline, 30% of patients were retired/unemployed, 36% were employed. At follow up, these patients had no change in status. Thirteen patients previously disabled were able to return to work. Three patients retired and work status did not change for 2 patients not working due to disability at baseline (ages 83 and 62).


SI joint symptoms can present as pain in the SI joint, low back, hip, groin, or buttock. As a result, a careful and thorough clinical and physical exam must be performed to correctly identify the pain generator. Positive provocative maneuvers combined with 75% pain relief after image guided SI joint injection(s) is a reliable method for diagnosing the SI joint as the pain generator [22, 23].

SI joint arthrodesis has been previously described as a treatment option for pain refractory to conservative care. As with many spinal conditions, there is no set standard protocol for conservative care in this population. Various methods are described in the literature and diagnostic standards typically include positive provocative maneuvers and/or pain relief after SI joint block [6, 12-16, 24-34]. Buchowski et al. reported significant improvements in pain and function as measured by SF-36 on 20 patients who underwent SI joint arthrodesis using a posterior modified Smith-Peterson technique [12]. The Smith Peterson technique involves excision of a 2.5 x 3.5cm iliac bone graft that is then secured within the SI joint using 6.5mm AO bone screws. Buchowski et al. modified this technique to remove the bone window directly over the SI joint, exposing the articular surface of the joint. The joint surface was curetted prior to graft reinsertion and fixation with plates and screws. Reported complications included a 15% nonunion rate that required revision using an anterior approach and two associated deep wound infections. Although open surgery may result in positive pain and function improvements, the procedure is invasive and comes with a high revision rate.

Arthrodesis using a percutaneous approach with screws or threaded cages has been described with positive results. Al-Khayer et al. reported on 9 patients using a single hollow modular anchorage (HMA) screw packed with bone graft [16]. All patients experienced a clinically significant improvement in VAS pain scores and all but 1 patient improved in function. One patient suffered a deep wound infection. Khurana at al. also report on an HMA with demineralized bone matrix in a cohort of 15 patients with relatively good outcomes [32]. Wise and Dall reported good clinical results after fusing 13 patients with an 11x25mm threaded cage packed with rhBMP-2 [17]. The cage was inserted posteriorly within the joint rather than across the joint as reported in previous studies. Due to the off-label nature and elevated cost associated with rhBMP-2, autologous iliac crest harvest was suggested. However, studies suggest that this can lead to further degeneration of the SI joint [12]. The various MIS methods described represent an improvement to the open surgical technique but leave room for improvement in technique and patient outcomes.

It is well known that minimally invasive methods for other surgical procedures have reduced peri-operative morbidity. Advantages of this reported MIS SI joint fusion implant technique include a small incision, minimal blood loss, bone and ligament preservation, and a relatively short period of immobilization.

The learning curve for this minimally invasive procedure was relatively low. Incision location was slightly modified based on two incidents of postoperative buttock hematoma. The etiology of these hematomas was postulated to be an injury to a branch of the superior gluteal artery due to an inferior/anterior approach on the buttock. The incision location was modified to allow for a more posterior penetration of the gluteal muscle without further incident of hematoma. Early on in our experience, a post-op pelvic CT scan was performed on all patients to assess implant placement. To avoid possible nerve root irritation, the implants should be seated central and anterior to the SI joint with particular attention paid to the depth of implant placement.

In our cohort of patients undergoing MIS SI joint fusion using the iFuse implant, clinical outcomes were favorable: 82% at 40 months experienced a clinically significant benefit. Mean improvements in quality of life measures were statistically and clinically significant at all time points. A comparison of previously reported literature reveals similar blood loss compared to other MIS techniques and as expected, lower rates of blood loss compared to open surgical procedures (Table 5). Patients in the current cohort reported a greater improvement in pain relief compared to historic controls at the 40-month follow up period. Pain scores improved by an average of 5.9 points (n=45) compared to 3.5 points (n=9) reported by Al-Khayer, and 4.9 points (n=13) reported by Wise at a similar time point [16, 17]. The complication rate in this cohort was 20%, which is average compared to the literature. It should be noted that half of these adverse events were minor requiring little if any intervention, including mild hematoma at incision site and superficial cellulitis. In addition, the revision rate of 8% after three years is comparatively low, particularly when taken in the context of the learning curve of a novel procedure.

Table 5.

Comparative Studies. All Studies are Consecutive Case Series

Author, Year N Demographics Diagnostic Standard Surgical Procedure/Post-Op Care Results Complications
Kibsgard, 2012 [33] 50, 28 Fusion (50 pts)
Age: 58
Gender: 47F/3M
Follow-up: 23 yrs
Unilateral 21/Bilateral 25
Dx: Post-partum (30), Trauma (8), Idiopathic (12)
Non-Surgery (28 pts)
Age: 52
Gender: 28F
Follow-up: 17 yrs
PSIS tenderness, positive straight leg raise, positive provocative maneuvers Trans-iliac fusion or intra/extra-articular fusion between the ilium and the sacrum using cortical iliac window and iliac crest autograft.
Post-op care: In most cases the patients were confined to 6 weeks of bed rest.
Surgical patients after 1 year: 24 (48%) patients were good, 12 (24%) were fair, and 14 (28%) were poor.
No significant difference in ODI, VAS, or SF-36 between surgery and non-surgery patients after long-term follow-up.
Reoperation: 7
Nonunion: 8
Jaundice: 1
Pulmonary embolism: 1
Pin tract infection: 1
Complication rate: 20%
Revision rate: 14%
Khurana, 2009 [31] 15 Age: 48.7 years
Gender 11F/4M
Follow-up: 17 months
Unilateral 11/Bilateral 4
Previous lumbar surgery: 6
Dx: Osteoarthritis (7), SI joint dysfunction(4), SI joint instability (3), Inflammatory Arthritis (1)
Tenderness over the posterior SI joint, positive provocative maneuvers, pain relief with SI joint block 10 mm Hollow Modular Anchorage Screw packed with demineralized bone matrix across the SI joint.
Post-op care: Partial weight bearing for six weeks and full weight bearing by 12 weeks.
Blood loss: < 50 ml
LOS 2.7 days
SF-36 increased: PF 37 to 80, GH 53 to 86
Majeed's: 37 to 79
Good/Excellent: 13/15
Fusion in all patients
None reported
Al-Khayer 2008 [16] 9 Age: 42 years
Gender: 9F
Follow-up: 40 mo
Unilateral 6 /Bilateral 3
Symptom Duration: 30 mo
Prior treatments: Failed conservative treatment
Dx: Chronic SI joint pain
Tenderness over the sacral sulcus, positive provocative maneuvers, X-rays to exclude other pain sources, relief from SI joint block 10 mm Hollow Modular Anchorage Screw packed with demineralized bone matrix across the SI joint.
Post-op care: early mobilization w/in pain limits
Blood loss: <50 ml
No screw loosening, nonunion, or failure
LOS: 6.9 days
Return to work: 4/9
ODI decreased: 59 to 45
VAS decreased: 8.1 to 4.6
Satisfaction: 6.8 (out of 10)
1 deep wound infection
Complication rate: 11%
Wise, 2008 [17] 13 Age: 53 years
Gender: 12F/1M
Follow-up: 29.5 mo
Unilateral 7/Bilateral 6
Previous lumbosacral surgery: 8/13
Prior treatments: Failed > 6 mo of conservative therapy
Relief with SI joint block 9mm hole drilled through the longitudinal aspect of the SI joint. 2 cages packed with BMP placed across the anterior portion of the SI joint.
Post-op care: limited waist bending, and a sacral belt for 6 mo; full activity at 6 mo
Blood loss: < 100 ml
Length of stay: 1.7 days
Fusion rate: 89%
Low back VAS improved 4.9 pts
Leg VAS improved 2.4 pts
Reoperation (nonunion): 1
Complication and Revision rate: 8%
Buchowski, 2005 [12] 20 Age: 45 years
Gender: 17F/3M
Follow-up: 5.8 yrs
Prior treatments: All failed nonoperative treatment
Previous spine surgery: 15/20
Symptom Duration: 2.6 yrs
Dx: SI joint dysfunction (13), Osteoarthritis (5), Spondyloarthropathy (1), SI joint instability (1)
Sacral sulcus palpation, positive provocative maneuvers, Pain relief with intraarticular SI joint injections Modified Smith-Petersen Incision over posterior 2/3 of iliac crests. Graft stabilized w/ plate and screws.
Post-op care: Non-weight bearing for at least 3 months.
Blood loss: 290 mL
Solid fusion: 17
LOS: 5.2 days
Return to work: 8/20
SF-36 improved (except GH & MH)
AAOS MODEMS sig. improved (except Comorbidity) 60% would have surgery again
Pseudoarthrosis: 3
Deep wound infection: 2
Painful hardware: 1
Revision surgery (anterior): 3
Complication rate: 30%
Revision rate: 15%
Giannikas, 2004 [13] 5 Age: 22 to 44 years
Gender: 3F/2M
Follow-up: 29 mo
Symptom Duration: 10 to 40 mo
Dx: Idiopathic (1), Previous trauma (4)
SI joint tenderness, positive provocative maneuvers, bone scan, relief with SI joint block Two bone plugs harvested from the iliac crest and placed through the superior and inferior aspects of the SI Joint.
Post-op care: Non-weight bearing for at least 3 months.
Complete pain relief: 4/5
Partial pain relief: 1/5
None reported
Moore, 1997 [15] 77 Gender: 48F/29 M
Unilateral 74/Bilateral 3
Prior treatments: Failed
6 months of rehab programs Symptom duration: 6 to 84 mo
Follow-up: 1 to 5 years
Dx: Chronic painful dysfunction
Relief with SI joint block Modified Smith-Petersen technique with 15cm incision to reveal the ilium and sacrum. Bone harvested from the ilium and placed in the SI joint after removing the cartilage. 2-3 cannulated screws to lock graft in place. Post-op care: Non-weight bearing for 8 weeks. 62/77 successful (80.5%) Superficial wound infection: 1
Post-op radicular pain: 1
Sciatic notch fracture: 1
Pseudoarthrosis: 7
Complication rate: 13%
Keating, 1995 [26] 26 Age: 38.3 years
Follow-up: 16 weeks
Prior treatments: Failed
6 weeks of aggressive rehab
Symptom duration: 38.3 mo
Dx: Chronic LBP
Relief with SI joint block Inferior SI joint debrided, decorticated, and packed with bone graft. Secured with 2 lateral compression screws.
Post-op care: 16 week rehabilitation program.
Pain decreased: 6.1 to 2.9
Work Status increased: 2.3 to 3.3
5 patients returned to work after 16 mo of unemployment
None reported
Waisbrod, 1987 [34] 21 Age: 42
Gender: 18F/3M
Follow-up: 30 mo
Previous spine surgery: 7/21
Symptom duration: > 2 years
Dx: SI joint pain
Tenderness over the SI joint, positive provocative maneuvers, pain provocation w/ NaCL injection, relief w/ SI joint block SI joint excised and packed w/ iliac crest bone graft and ceramic blocks.
Post-op care: Spica cast for 8 weeks.
11/21 Satisfactory results Pseudoarthrosis: 2
Infection: 1
Complication rate: 14%

To our knowledge, this is the largest known case series on SI joint fusion in the published literature to date. Limitations of this study include small sample size, single surgeon experience, a non-standard outcomes measure and absence of a comparator group. In our review of available literature on various SI joint fusion techniques, less than half of the case series reports used any standard validated outcomes tool. The small number of patients available at the 12-month interval compared to 6 months was due in part to our discharge procedure. As a private practice office, patients are routinely discharged after 6 months if there are no ongoing findings requiring investigation. For this study, patients were contacted and reported outcomes at 40-months.

This study also has strengths. All patients were from a single center, which ensured a consistent diagnostic and therapeutic approach. Our results validate the SI joint as a potential pain generator in patients with low back pain and previous lumbar fusion. Clinicians are encouraged to investigate the SI joint as a possible source of pain in order to avoid unnecessary repeat lumbar spine surgery. Prospective studies are currently underway to further evaluate this technology.


When conservative measures fail, minimally invasive SI joint fusion using a series of triangular porous plasma coated titanium implants is a safe and effective treatment option in carefully selected patients.


No funds were received in support of this research. The author hold stock in and is a consultant for SI-BONE, Inc., the manufacturer of the implant used in this study.


The author wishes to acknowledge Robyn Capobianco for data analysis and editorial review.


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