RESEARCH ARTICLE


The Use of Scaffolds in Musculoskeletal Tissue Engineering



Frances Henson1, Alan Getgood*, 2
1 Department of Veterinary Medicine, University of Cambridge, Cambridge, CB3 0ES, UK
2 The Fowler Kennedy Sport Medicine Clinic, The University of Western Ontario, Ontario, Canada


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Creative Commons License
© Henson and Getgood; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Fowler Kennedy Sport Medicine Clinic, The University of Western Ontario, Ontario, Canada; Tel: +1 (0) 4036 097286; Fax: +1 (0) 4036 097285; E-mail: agetgood@btinternet.com


Abstract

The use of bioengineering scaffolds remains an integral part of the tissue engineering concept. A significant amount of basic science and clinical research has been focused on the regeneration of musculoskeletal tissues including bone, articular cartilage, meniscus, ligament and tendon. This review aims to provide the reader with a summary of the principals of using material scaffolds in musculoskeletal tissue engineering applications and how these materials may eventually come to be incorporated in clinical practice.

Keywords: Musculoskeletal tissue engineering, scaffolds.