Quantitative Assessment of Improvement with Single Corticosteroid Injection in Thumb CMC Joint Osteoarthritis?

Munir Khan*, Mohammad Waseem, Ali Raza, Damjana Derham
Macclesfield General Hospital, Victoria Road, Macclesfield SK10 3BL, UK

Article Metrics

CrossRef Citations:
Total Statistics:

Full-Text HTML Views: 969
Abstract HTML Views: 276
PDF Downloads: 159
Total Views/Downloads: 1404
Unique Statistics:

Full-Text HTML Views: 535
Abstract HTML Views: 212
PDF Downloads: 122
Total Views/Downloads: 869

Creative Commons License
© Khan et al.; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Macclesfield General Hospital, Victoria Road, Macclesfield SK10 3BL, UK; E-mail:


We present a unique prospective study to estimate the median sustained stage-related improvement in pain and hand function in patients with trapezio-metacarpal joint osteoarthritis after administration of a single corticosteroid injection. Response to the corticosteroid injection was assessed using Disability of Arm Shoulder and Hand (DASH) and Visual Analogue Scale (VAS) pain scores. Self assessment scores revealed a reduction in pain and improvement in hand function. All patients reported a significant improvement in pain and hand function (p ≤ 0.05), regardless of the disease stage. Additionally, we observed a marked difference in the duration of improvement in hand function between early and late stages of the disease (p = 0.0046). In conclusion, it is possible to predict the period of symptomatic improvement at each of the four radiological stages of the disease. This would allow the treating clinician to judge the outcome of treatment with reasonable accuracy.