Carbon Nanostructures in Bone Tissue Engineering
Brian Lee Perkins1, *, Naghmeh Naderi2, 3
Identifiers and Pagination:Year: 2016
Issue: Suppl-3, M7
First Page: 877
Last Page: 899
Publisher ID: TOORTHJ-10-877
Article History:Received Date: 16/10/2015
Revision Received Date: 15/11/2015
Acceptance Date: 31/05/2016
Electronic publication date: 30/12/2016
Collection year: 2016
open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
Recent advances in developing biocompatible materials for treating bone loss or defects have dramatically changed clinicians’ reconstructive armory. Current clinically available reconstructive options have certain advantages, but also several drawbacks that prevent them from gaining universal acceptance. A wide range of synthetic and natural biomaterials is being used to develop tissue-engineered bone. Many of these materials are currently in the clinical trial stage.
A selective literature review was performed for carbon nanostructure composites in bone tissue engineering.
Incorporation of carbon nanostructures significantly improves the mechanical properties of various biomaterials to mimic that of natural bone. Recently, carbon-modified biomaterials for bone tissue engineering have been extensively investigated to potentially revolutionize biomaterials for bone regeneration.
This review summarizes the chemical and biophysical properties of carbon nanostructures and discusses their functionality in bone tissue regeneration.