REVIEW ARTICLE
Knee Arthritis Without Other Joint Symptoms in the Elderly With Seronegative Elderly Onset Rheumatoid Arthritis
Takatomo Mine*, Koichiro Ihara, Hiroyuki Kawamura, Ryutaro Kuriyama, Ryo Date
Article Information
Identifiers and Pagination:
Year: 2016Volume: 10
First Page: 793
Last Page: 796
Publisher ID: TOORTHJ-10-793
DOI: 10.2174/1874325001610010793
Article History:
Received Date: 20/10/2016Revision Received Date: 21/11/2016
Acceptance Date: 23/11/2016
Electronic publication date: 30/12/2016
Collection year: 2016

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
Abstract
Elderly onset Rheumatoid arthritis (EORA) has important clinical distinctions when compared with younger onset RA (YORA). In knee arthritis of elderly patients, infection, crystal-induced arthritis or EORA should be suspected if elevation of CRP in the preoperative examination and turbid joint effusion in their knee joint are found. Furthermore, if joint swelling and effusion remain after performing total knee arthroplasty (TKA), the infection after TKA, implant debris-related arthritis and EORA should be considered. However, it is difficult to diagnose patients as EORA if Rheumatoid factor (RF) and anti-cyclic citrullinated peptide antibody (ACPA) are negative. The differential diagnosis is very important.