Dupuytren's Disease: Review of the Current Literature

Morsi Khashan*, 1, Peter J Smitham 2, Wasim S Khan 3, Nicholas J Goddard 2
1 Orthopedic Surgery Department, Tel-Aviv Soursky Medical Center, Tel-Aviv, Israel
2 Department of Trauma and Orthopaedics, Royal Free Hospital, Royal Free Hamstead NHS Trust, Pond Street, London, NW3 2QG, UK
3 University College London Institute of Orthopaedics and Musculoskeletal Sciences, Royal National Orthopaedic Hospital, Stanmore, Middlesex, HA7 4LP, UK

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© Khashan et al.; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Orthopedic Surgery Department, Tel-Aviv Soursky Medical Center, Tel-Aviv, Israel; Tel: +97236974724; Fax: +97236974736; E-mail:


Dupuytren’s disease is one of the most common condition seen by hand surgeons. It is not only prevalent but can also be a most debilitating condition resulting in significant loss of function of the fingers involved. The cause of this disease, however still remains largely unknown although some recent evidence suggests a stem cell etiology. This review article summarizes the current known knowledge of Dupuytren’s as well as the clinical findings, investigations and treatments available.

Keywords: Contracture, Dupuytren’s disease, Dupuytren’s nodules, fasciectomy, hand.