RESEARCH ARTICLE


Freezing of Rat Tibiae at -20°C Does Not Affect the Mechanical Properties of Intramedullary Bone/Implant-Interface: Brief Report



Michael Diefenbeck*, 1, Thomas Mückley1, Sergiy Zankovych2, Jörg Bossert2, Klaus D Jandt2, Christian Schrader3, Jürgen Schmidt3, Ulrich Finger4, Mathilde Faucon4
1 Klinik für Unfall-, Hand- und Wiederherstellungschirurgie, Universitätsklinikum Jena, Erlanger Allee 101, D-07747 Jena, Germany
2 Institute of Materials Science and Technology (IMT), Friedrich-Schiller-Universität Jena, Löbdergraben 32, D-07743 Jena, Germany
3 Innovent Technology Development, Prüssingstraße 27 B, D-07745 Jena, Germany
4 Königsee Implantate GmbH, OT Aschau - Am Sand 4, D-07426 Allendorf, Germany


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Creative Commons License
© Diefenbeck et al.; Licensee Bentham Open.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Klinik für Unfall-, Hand- und Wiederherstellungschirurgie, Universitätsklinikum Jena, Erlanger Allee 101, 07747 Jena, Germany; Tel: 0049 3641 9 322800; Fax: 0049 3641 9 322802; E-mail: Michael.Diefenbeck@med.uni-jena.de


Abstract

Background:

The effects of freezing-thawing cycles on intramedullary bone-implant interfaces have been studied in a rat model in mechanical pull-out tests.

Implants:

Twenty TiAl6V4 rods (Ø 0.8 mm, length 10 mm) implanted in rat tibiae

Methods:

10 rats underwent bilateral tibial implantation of titanium rods. At eight weeks, the animals were sacrificed and tibiae harvested for biomechanical testing. Eight tibiae were frozen and stored at -20°C for 14 days, the remaining eight were evaluated immediately post-harvest. Pull-out tests were used to determine maximum force and interfacial shear strength.

Results:

There were no significant differences between fresh and those of the frozen-thawed group in maximum force or in interfacial shear strength.

Conclusion:

Frozen Storage of rat tibiae containing implants at -20° C has no effects on the biomechanical properties of Bone/ Implant interface.

Keywords: Bone, implant, bone-implant-interface, fixation, freezing/thawing cycles, storage.