Definition of Periprosthetic Hip and Knee Joint Infections and the Economic Burden

Rosamond Tansey1, *, Yusuf Mirza1, Mohamed Sukeik2, Mohammed Shaath3, Fares Sami Haddad1
1 Department of Trauma and Orthopaedics, University College London Hospital, 235 Euston Road, NW1 2BU, London, United Kingdom
2 Department of Trauma and Orthopaedics, The Royal London Hospital, Whitechapel, London, E1 1BB, United Kingdom
3 Department of Trauma and Orthopaedics, North Manchester General Hospital, Delaunay’s Road, Crumpsall, M8 5RB, United Kingdom

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© Tansey et al.; Licensee Bentham Open

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (, which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Department of Trauma & Orthopaedics University College Hospital London, 235 Euston Road, NW1 2BU, London, United Kingdom; Tel: 07779269010; E-mail:


Periprosthetic Joint infection (PJI) following hip and knee replacements is an important complication causing major concern for patients, operating surgeons and healthcare systems. Therefore, a standardized definition of PJI is required to improve communication and allow for valid comparisons of various diagnostic and treatment strategies. This review summarizes the most commonly used definitions for PJI and the current consensus. It also highlights the economic burden related to PJIs and the importance of a multidisciplinary approach to managing those infections.

Keywords: Consensus, Definition, Periprosthetic Joint Infection, Total Hip Arthroplasty, Total Knee Arthroplasty.