Biofilm and the Role of Antibiotics in the Treatment of Periprosthetic Hip and Knee Joint Infections
Yusuf H. Mirza1, *, Rosamond Tansey1, Mohamed Sukeik2, Mohammed Shaath3, Fares Sami Haddad1
Identifiers and Pagination:Year: 2016
Issue: Suppl-2, M6
First Page: 636
Last Page: 645
Publisher ID: TOORTHJ-10-636
Article History:Received Date: 12/03/2016
Revision Received Date: 17/06/2016
Acceptance Date: 15/07/2016
Electronic publication date: 30/11/2016
Collection year: 2016
open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
An increasing demand for lower limb arthroplasty will lead to a proportionate increase in the need for revision surgery. A notable proportion of revision surgery is secondary to periprosthetic joint infections (PJI). Diagnosing and eradicating PJI can form a very difficult challenge. An important cause of PJI is the formation of a bacterial biofilm on the implant surface. Our review article seeks to describe biofilms; their definitions and formation, common causative bacteria, prophylactic and therapeutic antibiotic therapy.