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Biofilm and the Role of Antibiotics in the Treatment of Periprosthetic Hip and Knee Joint Infections
Yusuf H. Mirza1 , *
Rosamond Tansey1
Mohamed Sukeik2
Mohammed Shaath3
Fares Sami Haddad1
Authors Info & Affiliations
Rosamond Tansey1
Mohamed Sukeik2
Mohammed Shaath3
Fares Sami Haddad1
Authors Info & Affiliations
Abstract
An increasing demand for lower limb arthroplasty will lead to a proportionate increase in the need for revision surgery. A notable proportion of revision surgery is secondary to periprosthetic joint infections (PJI). Diagnosing and eradicating PJI can form a very difficult challenge. An important cause of PJI is the formation of a bacterial biofilm on the implant surface. Our review article seeks to describe biofilms; their definitions and formation, common causative bacteria, prophylactic and therapeutic antibiotic therapy.
Keywords: Antibiotics, Biofilm, Periprosthetic joint infection, Total hip arthroplasty, Total knee arthroplasty.
