Post Traumatic Diffuse Neurofibroma in the Foot: An Unusual Presentation

Ahmed Abdul Hadi Nasser*, 1, Rashad Khamis Awad1, Fahad Alkhalifa1, Sara Al-Saad2
1 Department of Orthopaedics, Bahrain Defence Force Hospital – Royal Medical Services, Riffa, Kindgom of Bahrain
2 Department of Pathology, Bahrain Defence Force Hospital – Royal Medical Services, Riffa, Kingdom of Bahrain



Neurofibromas are benign peripheral nerve sheath tumors that present as solitary or multiple lesions. They can present alone or as part of the disease process called neurofibromatosis type 1. The etiology behind solitary neurofibromas is still poorly understood, however, trauma has been proposed to be a possible cause.


We present a rare case of a 23-year-old male, without any known medical history, who fell and injured his left foot 3 years prior to presentation. He was treated conservatively at that time and presented to Bahrain Defence Force hospital complaining of a progressive painless swelling in his left forefoot post trauma.


The patient underwent imaging studies, which misdiagnosed the lesion as a possible lymphangioma, haemangioma, or a chronic inflammatory swelling. An excisional biopsy was taken, and the pathology specimen proved the lesion to be a diffuse neurofibroma.


Trauma may possibly be a predisposing factor behind the development of solitary diffuse neurofibromas in patients that are not known to have neurofibromatosis. Further studies should be conducted to prove whether or not trauma is a predisposing factor for the development of solitary neurofibromas.

Keywords: Neurofibroma, Neurofibromatosis, Nerve sheath neoplasms, Schwann cells, Post-traumatic, Unusual presentation.

Abstract Information

Identifiers and Pagination:

Year: 2018
Volume: 12
Publisher Item Identifier: EA-TOORTHJ-2018-28

Article History:

Received Date: 23/06/2018
Revision Received Date: 15/10/2018
Acceptance Date: 30/10/2018
Electronic publication date: 15/11/2018
Collection year: 2018

© 2018 Nasser et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at the Department of Orthopaedics, Bahrain Defence Force Hospital – Royal Medical Services, Riffa, Kindgom of Bahrain; Tel:97333141339; E-mail: